CBD Overdose - Can You Overdose on CBD?
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Time to read 7 min
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Time to read 7 min
Cannabidiol (CBD) is derived from the hemp plant and has gained increasing popularity in recent years as a non-psychoactive component of cannabis. Many people use it to relieve various symptoms and conditions - from insomnia and anxiety to chronic pain. However, some wonder if it's possible to overdose on CBD and what effects too high a dosage could have.
The concern of a CBD overdose is often based on the fact that CBD is a cannabinoid from the hemp plant - just like the generally more well-known THC. In contrast to CBD, the cannabinoid THC has psychoactive effects and can indeed be overdosed. A classic overdose of CBD, however, is not possible.
"CBD generally has a good safety profile and is well tolerated," according to the World Health Organization WHO¹
If you take too much CBD, mild side effects may occur. However, this does not constitute a classic overdose. Nevertheless, it makes sense to consider general precautions and potential side effects when taking CBD. It is also important to find the ideal form of intake and dosage for yourself.
From a scientific perspective, there is no clear indication of how much CBD is actually too much, as tolerance depends heavily on individual factors. However, it is reported that dosages of up to 1500 mg per day can be well tolerated, provided they are taken under controlled and medically supervised conditions.² Such high dosages are usually limited to the therapeutic range and are monitored by a doctor.
For the average user of CBD products like CBD oil, it would be unusual and probably too expensive to consume such high amounts of CBD. Here's an example: to take 1500 mg of CBD, you would have to consume more than an entire 10 ml bottle of CBD oil in one day, depending on the specific concentration of the oil. This is not only expensive but also medically unnecessary, as there is enough evidence that lower dosages are sufficient for general well-being improvement.
Most CBD users consume between 0.5 and 20 mg daily to achieve positive effects. Higher dosages do not usually mean better or more effective results - quite the opposite.
Several studies have already been conducted on how the body reacts to high doses of cannabidiol.
A study from the Brazilian Journal of Medical and Biological Research in 2006 investigated the effects of daily CBD doses between 10 and 400 mg over a period of 30 days in healthy individuals. No signs of overdose or toxic reactions were observed.³
A 2018 study went even further and tested the tolerability of very high CBD doses. Healthy participants received between 1500 and 1600 mg of CBD daily. Generally, good tolerability was also observed here, although some participants experienced side effects such as headaches, diarrhea, or nausea.
If you take too much CBD, various side effects can occur:
Feeling unwell because you've taken too much CBD? The following steps can help you improve your well-being:
When choosing the right CBD dosage, the principle "less is more" is often helpful. Start with a small amount of CBD and gradually increase the amount to find the optimal dose for your individual needs.
CBD oil is usually sold in 10 ml bottles with a dropper for dosing. Just a few drops can be enough to achieve an effect. The body needs time to get used to CBD, so it's important to start with a low dose and gradually increase it. To start, it is recommended to take two drops daily for one week, ideally split into one drop twice a day. If no improvement in well-being is noticeable after this week, the dose can be gradually increased.
The concentration of the CBD oil also plays a role. Beginners should start with a CBD oil with a low CBD content and increase the dosage later if necessary.
| 5% CBD Oil | Approx. 1.52 mg CBD per drop |
| 10% CBD Oil | Approx. 3.04 mg CBD per drop |
| 15% CBD Oil | Approx. 4.56 mg CBD per drop |
| 20% CBD Oil | Approx. 6.08 mg CBD per drop |
| 25% CBD Oil | Approx. 7.6 mg CBD per drop |
| 30% CBD Oil | Approx. 9.12 mg CBD per drop |
Microdoses are between 0.5 and 20 mg of CBD per day. This dosage is often sufficient to promote general well-being. However, the ideal daily dose depends heavily on individual needs and can vary between 10 and 1000 mg of CBD. Since the optimal dose is very individual, a trial-and-error method⁴ is often recommended, where you gradually find the right dose.
The form of CBD intake can also play a role in finding the optimal CBD dosage and effect for you. Choosing the best form of intake depends on your personal preference and needs. There is a variety of CBD products, and each has its advantages and disadvantages. The following forms of intake are available:
Each form of intake has its own onset and duration of action. While CBD oil and sprays, for example, act quickly, capsules offer a gentler, delayed effect. It is worth trying different forms to find out what works best for you.
When selecting and taking CBD products, there are some important precautions you should observe to ensure you don't harm your body:
Similar to humans, dogs, cats, horses, and other mammals also have the so-called endocannabinoid system (ECS). Thus, they can also benefit from the positive effects of CBD.
Studies³ indicate that controlled administration of CBD in animals is as safe as in humans. However, as a precaution, especially for cats, it should be ensured that the CBD product contains no traces of THC. It could also be that animals generally react a bit more sensitively to CBD than humans, as they have a higher content of cannabinoid receptors in the brain.
Too much CBD can cause the same side effects in animals as in humans. It is therefore important to start with a low dose and increase it only if necessary and slowly. When taken in combination with other medicines, the intake should always be discussed with a veterinarian.
In summary, according to current research, a classic overdose of cannabidiol (CBD) is not possible. Studies indicate that even high CBD dosages of up to 1500 mg per day can be well tolerated under controlled conditions. However, such high dosages are more in the therapeutic range and far exceed the usual daily intake of CBD, which is mostly between 0.5 and 20 mg.
If you take too much CBD, mild side effects may occur. However, these are usually harmless and short-lived. When choosing a product, pay attention to quality and adhere to the recommended dosage. It is best to start with a microdose and increase the dose step by step if necessary. If you are taking other medications, it is advisable to discuss potential interactions with your doctor.
Sources and Studies
¹ WHO. Cannabidiol (CBD). Critical Review Report. Downloaded January 23, 2024. [Source]
² Mateus Machado Bergamaschi, Regina Helena Costa Queiroz, Antonio Waldo Zuardi, José Alexandre S Crippa. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Downloaded January 23, 2024. [Source]
³ Brazilian Journal of Medical and Biological Research. Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Downloaded January 23, 2024. [Source]
⁴ Frankhauser, M. & Eigenmann, D. (2020). Geschichte – Praxis – Perspektiven. Cannabis in der Medizin. Solothurn: Nachtschattenverlag.