CBD for Rheumatism: How it Works, What it Does
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Time to read 6 min
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Time to read 6 min
The term "rheumatism" encompasses various diseases such as rheumatoid arthritis, osteoarthritis, gout, and other inflammatory or degenerative joint and muscle conditions. In Germany, around 17 million people suffer from one or more forms. Not only elderly people are affected, but also younger adults and even children.
In their search for relief, many sufferers are now looking with great hope to cannabinoids like THC or CBD (cannabidiol). We will examine the current study situation and show how CBD can be used specifically to improve well-being and reduce the need for painkillers.
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Cannabidiol (CBD) products are considered very promising for the treatment of rheumatism. They have a primarily anti-inflammatory effect and thus help to relieve pain and possibly even slow down the course of the disease.
Unlike THC, which has a greater pain-relieving effect but comes with many side effects, CBD is very mild and is neither psychoactive nor addictive.
If CBD is taken in combination with other medications, the treating physician should always be consulted before use.
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Rheumatism is a chronic disease that affects the immune system and joints, leading to pain, stiffness, and inflammation of the entire musculoskeletal system. Especially in autoimmune forms like rheumatoid arthritis, the immune system attacks the body's own structures, leading to persistent joint pain.
In addition to conventional medicines and treatment methods, many sufferers are now interested in natural alternatives to improve their quality of life. Cannabidiol (CBD), as a non-psychoactive component of the hemp plant, has received a lot of attention in recent years.
Research focuses on the one hand on the possible pain relief through CBD and on the other hand on its anti-inflammatory effect.
While pain relief is now primarily associated with CBD's psychoactive "sister," tetrahydrocannabinol (THC), CBD is considered a very good option for relieving inflammation and thus a particularly sustainable treatment.
Results from cannabis research and experiences from doctors and patients indicate that CBD interacts with the body's own endocannabinoid system (ECS). The ECS consists of receptors found throughout the body, but especially in immune and nerve cells. CBD is thought to act on CB1 and CB2 receptors, which are associated with pain and inflammation modulation. By influencing these receptors, CBD can inhibit inflammatory processes, such as those that occur in rheumatic diseases. This can reduce the intake of painkillers and increase the general quality of life of affected individuals.
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Studies¹ show the anti-inflammatory effect of CBD. It can inhibit the production of pro-inflammatory cytokines, thereby reducing inflammation in the body. CBD can lower inflammation levels in patients with rheumatoid arthritis, which could positively influence the course of the disease. Since inflammation is a main cause of joint damage in rheumatism, CBD can thus help to slow down the progression of the disease in the long term.
While the anti-inflammatory effects of CBD are well-researched, there are still gaps in research regarding its pain-relieving effects.² THC is generally better studied in this regard. However, the experiences of pain patients show that CBD can also relieve pain.
Studies suggest that CBD can exert a pain-relieving effect by influencing CB1 and CB2 receptors. One study³ showed that CBD significantly reduced pain and inflammatory symptoms in animal models of arthritis. Many users also report that CBD noticeably alleviates joint stiffness and everyday pain.
Chronic diseases, pain, and sleep problems often go hand in hand. Lack of sleep can increase pain sensitivity and vice versa. CBD has a calming effect and can improve sleep quality, which can indirectly reduce pain perception. Studies⁴ have shown that CBD has calming effects on the nervous system and can positively influence the sleep-wake rhythm.
Many affected individuals report feeling less stressed and generally more balanced with CBD. In rheumatoid arthritis, which is often accompanied by high psychological stress because pain and restricted movement affect daily life, this can be of great importance. By relieving the body and mind, the general quality of life improves, and the burden of the disease can be perceived as less severe.
Although most users describe CBD as very well tolerated, side effects can occur in rare cases. Possible side effects include dry mouth, slight dizziness, and occasionally stomach discomfort. It is also important to note that CBD can interact with other medications, especially those used for rheumatism. You should definitely discuss this with your treating physician beforehand to clarify possible interactions.
For some people, taking CBD also requires a bit of getting used to. Sublingual administration (drops under the tongue) is often unfamiliar at first, and the strong hemp taste is not for everyone. Cannabis sprays like our CBD Lemon Mint Spray can help you get used to taking it. Especially for rheumatism, topical oils and creams that are applied to the skin and massaged in can help alleviate symptoms.
It is important to find the right dosage for your body for optimal pain defense. Ideally, start with a low dosage and then increase it until you have found the right dose for you. We recommend taking CBD over a longer period to achieve optimal long-term effects.
Even though both are cannabis products, i.e., products from the hemp plant: CBD and THC have very different properties and effects. THC, unlike CBD, is psychoactive and can have severe side effects. It is not without reason that CBD oils and other products are freely available in Germany, while a prescription from a doctor is required for cannabis therapy with THC.
Criterion |
THC |
CBD (Cannabidiol) |
Effect on pain |
Strong pain-relieving effect, suitable for acute pain |
Moderate pain relief, often effective for chronic pain |
Anti-inflammatory |
Has anti-inflammatory effects, but less strong than CBD |
Strong anti-inflammatory effect |
Psychoactive effects |
Psychoactive; causes intoxication and euphoria |
Not psychoactive; no high |
Side effects |
Severe side effects possible; can cause anxiety, paranoia, and drowsiness |
Mild symptoms: Occasionally dry mouth, low blood pressure, fatigue |
Legal availability |
Prescription-only in Germany |
Legally available as a dietary supplement (max. 0.2% THC) |
Application area |
Suitable for severe, treatment-resistant rheumatic pain |
Supportive for mild to moderate rheumatic symptoms |
For rheumatic complaints, we recommend applying higher-dosed CBD oil (e.g., 30% full-spectrum oil) or cream to the affected joints to locally relieve pain. Long-term, inflammatory processes in the body can be alleviated by taking CBD oil. Additionally, CBD oil can help to improve sleep and thus enhance overall quality of life.
Overall, CBD is a promising candidate for the complementary treatment of rheumatism and similar conditions (e.g., fibromyalgia). Through its anti-inflammatory and pain-relieving effects, CBD can help affected individuals reduce the limitations caused by the disease and improve their quality of life.
Even though human research is still ongoing, several studies in recent years indicate that CBD can have a supportive effect on chronic inflammation. For many rheumatism patients seeking natural relief for their symptoms, CBD can thus be a real game-changer.
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Sources and Studies
¹ Paland N, Hamza H, Pechkovsky A, Aswad M, Shagidov D, Louria-Hayon I. Cannabis and Rheumatoid Arthritis: A Scoping Review Evaluating the Benefits, Risks, and Future Research Directions. Rambam Maimonides Med J. 2023 Oct 29;14(4).
² Cásedas F, Pérez LM, Sáez JA, et al. Cannabidiol for Pain Management: Current Evidence and Future Directions. Pharmaceuticals. 2024 Feb;17(2):233.
³ Hammell DC, Zhang LP, Ma F, Abshire SM, McIlwrath SL, Stinchcomb AL, Westlund KN. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. European Journal of Pain. 2016 Jul;20(6):936-948.
⁴ Chagas MH, Eckeli AL, Zuardi AW, et al. Cannabidiol Can Improve Complex Sleep-Related Behaviors Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson's Disease Patients: A Case Series. Journal of Clinical Pharmacy and Therapeutics. 2014;39(5):564-566.