Frau mit Kopfschmerzen

CBD for headaches: Why it works so well

Written by: Anne Ullrich

|

Time to read 11 min

You probably know the feeling: you wake up in the morning and your head already hurts. Or you come home after a long day at work and feel the pain spreading from your neck to your head. Headaches are among the most common complaints that plague people. Especially with our stressful everyday lives, they almost seem to be a part of it: In Germany, about 52% of men and 67% of women suffer from headaches at least once a year.

Classic reaction to a headache? Reaching for a painkiller. But: Especially with long-term use, common painkillers like aspirin, paracetamol, or ibuprofen can have severe side effects. Hemp products and cannabinoids like CBD have long been discussed as a possible alternative therapy for pain, including headaches. We'll examine how effective CBD is against headaches and why it works so well.

The most important things at a glance

While classic painkillers only suppress symptoms, CBD directly addresses the causes of tension headaches. It relaxes muscles, relieves stress, and naturally regulates pain perception.

Unlike aspirin, ibuprofen, and the like, which can strain the stomach, liver, and kidneys with prolonged use, no serious long-term damage is known with CBD, even with regular use. Neither addiction effects nor medication-induced headaches occur.

For optimal results, a full-spectrum CBD oil in drop or spray form is recommended. Start with 5-10 mg daily and gradually increase the dose if needed. The full effect usually develops after 2-4 weeks of regular intake.

Not all headaches are the same

First of all: Not every headache is a migraine, even if we often use the terms migraine and headache synonymously. In medicine, more than 200 types of headaches are distinguished. The most important are tension headaches, migraines, and (rarely) cluster headaches.

Tension headaches are by far the most common. Almost everyone knows that dull, throbbing feeling, as if someone is pressing on your forehead or temples. The pain is usually on both sides and in most cases comes from tense shoulder and neck muscles - even if many sufferers don't directly perceive it. Stress, a lot of screen work, poor posture, and too little exercise are typical triggers for this type of headache. Because they are so common, in this article we mainly deal with tension headaches.

Migraine, on the other hand, is a neurological condition. The pain is pulsating and one-sided - hence the name "migraine," which means "half a head." Many people also suffer from nausea and vomiting, and are particularly sensitive to light and noise. Migraine attacks can last several hours or even days. In another article here on the blog, we've already looked at how CBD can help with migraines. More about CBD for migraines.

Cluster headaches are rather rare. But their intensity is all the more severe. Cluster headaches occur in attacks, usually starting on one side of the head around the eye. Sufferers report several pain episodes within a short period (up to 8 times a day, each lasting between 15 minutes and 3 hours). Then it can happen that no more attacks occur for quite a while. The pain is extremely strong, and the disease is not curable. However, there are now ways to alleviate the pain.

Infographic: How tension headaches arise

Why we primarily talk about tension headaches

We do not mean to imply that migraines or cluster headaches are not extremely painful and severely limit the daily lives of sufferers. However, most people suffer from tension headaches.

In addition, tension headaches respond particularly well to natural treatments that address the cause, such as promoting relaxation and stress reduction. And that's where CBD comes in.

Classic painkillers: The quick pill

In Germany, many painkillers are available without a prescription. For headaches, many reach for ibuprofen, paracetamol, or ASA (aspirin). They work quickly, are available in every pharmacy, and initially seem harmless. But are they really?

How conventional painkillers work

Most over-the-counter pain medications belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) or are analgesics like paracetamol. They block the formation of prostaglandins, messenger substances that transmit pain signals to the brain and promote inflammation. This suppresses our perception of pain.

Side effects with long-term use

In principle, there is nothing wrong with taking a tablet for headaches now and then. (However, be careful if you want to donate blood or if surgery is imminent. Your doctor will advise you and discuss everything during the preliminary consultation.)

It becomes problematic if you take painkillers regularly. Especially when tension headaches recur repeatedly (e.g., because living conditions do not change), some people tend to take pain medication very frequently.

Typical side effects include stomach ulcers from NSAIDs (e.g., ibuprofen). They also strain the liver and kidneys and can increase the risk of cardiovascular diseases with long-term use. Paracetamol, in turn, can be toxic to the liver at too high a dose - with sometimes serious consequences.

In addition, with regular intake, the receptors "get used" to the painkiller, and you need more and more to achieve the same effect.

MOH - Medication Overuse Headache

Still relatively little known, but not uncommon: Did you know that headache tablets can give you headaches? This is also called "rebound headache." The causes are not yet fully understood. What is certain is that affected individuals often resort to tablets more and more frequently, which gradually makes the situation worse. The best remedy for MOH: withdrawal (in severe cases with medical support).

The effects of CBD

CBD (cannabidiol) is a natural active ingredient from the hemp plant, a so-called cannabinoid. Unlike THC, which has psychoactive effects and thus triggers the well-known "high" feeling when consuming cannabis, CBD has a very gentle effect. In Germany, it can be legally purchased and consumed as a dietary supplement.

In recent years, interest in CBD has massively increased. Research is now also taking a very close look. And not without reason. It is now known that cannabinoids like CBD interact with our body's own endocannabinoid system (ECS). This is a huge network of receptors and neurotransmitters that, among other things, regulates our pain perception (and our sleep, muscle tension, stress processing, inflammatory reactions, and much more).

hanfgeflüster CBD Oils

CBD for Headaches

Various studies have examined how exactly CBD works against pain. For tension headaches, several effects of CBD come into play:

  • CBD has a relaxing effect on muscles. Cannabis products like CBD are known to relieve muscle cramps, e.g. in muscle spasms (1), but also in less severe tension, e.g. due to poor posture or lack of movement.

  • CBD inhibits inflammation. Chronic muscle tension in the shoulders and neck can trigger inflammatory processes in the body, which in turn can lead to pain. Studies show that cannabinoids like CBD can act against inflammation. (2)

  • CBD relieves stress. Stress is one of the main causes of tension headaches. Studies and customer experiences show that CBD calms the nervous system, relieves stress, and helps improve overall well-being. It does not cause drowsiness or grogginess like many painkillers.

  • CBD reduces pain. CBD directly influences our pain perception via the endocannabinoid system. This can dampen the pain signals transmitted to the brain and can therefore be as effective as conventional medications – almost entirely without side effects and completely naturally.

  • CBD promotes sleep. Many users report that CBD oil helps them fall asleep and stay asleep better, which can positively impact their migraine and headache attacks.

Side effects and interactions of CBD

CBD oil usually has only minor side effects, which can vary individually. Typical effects include fatigue, dizziness, and dry mouth. However, these side effects can usually be easily remedied by reducing the dose. Unlike many medications, no long-term damage from CBD is known. You also don't have to worry about habituation effects or even addiction. Even the WHO states that cannabidiol poses no risk of dependence.

However, CBD is metabolized by the liver - similar to Ibuprofen and co. The effect of CBD oil varies individually, and we recommend discussing its use with a doctor, especially if you are taking other medications.

The direct comparison: Painkillers vs. CBD products

The following table provides a good overview of the effects, as well as the advantages and disadvantages of CBD vs. classic medications.

Criterion

Classic Painkillers (e.g. Ibuprofen, Aspirin, Paracetamol)

CBD Products

Purpose of Use

Acute pain relief

Supportive regulation of pain, stress, and muscle tension

Mechanism of Action

Inhibition of prostaglandins → reduced pain and inflammation signals

Modulation of the endocannabinoid system, influence on pain processing and stress axes

Onset of Action

Rapid (approx. 15–30 minutes)

Gradual (approx. 30–90 minutes, depending on form)

Suitability for Acute Pain

Very suitable

More complementary, not primarily for acute pain peaks

Suitability for Recurrent Tension Headaches

Short-term effective, problematic with frequent use

Potentially useful as part of a long-term, holistic approach

Side Effects (short-term)

Gastrointestinal discomfort, nausea possible

Mostly mild (e.g., fatigue, dry mouth)

Risks with Long-term Use

Gastric, liver, kidney strain, MOH risk

Long-term data limited, no typical analgesic risks known so far

Habituation / Rebound Headache

Possible with frequent use

No evidence of MOH so far

Interactions

Numerous, especially with blood thinners & other painkillers

Possible via liver enzymes (CYP450)

Prescription Requirement

No (standard dosage)

No

Role in Therapy Concept

Short-term symptom treatment

Complementary measure for stress reduction, exercise, and prevention

Infografik: CBD and painkillers in comparison

How to use CBD oil correctly

Using CBD for pain relief is surprisingly simple. The important thing is to find the right dose and product for you.

Our dosage calculator is the first place to start to find a good dosage for your needs. In general, less is often more, and every body reacts differently. Start with a low dose of about 5-10 mg of CBD per day. For a 5 percent oil, this corresponds to approximately 2-4 drops.

Take this dose consistently for a few days and observe how your body reacts. If you don't feel sufficient improvement after a week, gradually increase the dose by 5 mg until you achieve the optimal effect. Most people with tension headaches do well with 15-30 mg of CBD per day.

For acute headaches, you can use a slightly higher dosage (e.g., more drops at the same concentration). In the long term, you should make CBD part of your daily routine to help relax your muscles and regulate your nervous system. In combination with other relaxation techniques such as meditation, yoga, or endurance sports, CBD is particularly effective.

CBD for Headaches: What Our Customers Say

Many of our customers have had positive experiences using CBD for headaches. Here are a few excerpts from our Trustpilot reviews.

"After a few applications (menstrual pain, stuffy nose, headaches), I can say, wow, it helps me well to make the pain more bearable or to make it go away." (Source: Trustpilot)

Sabine S., June 14, 2024

"I bought the 15% CBD oil for my daughter, who often gets headaches from stress, and it helps her wonderfully. Ibuprofen is not for her because it attacks her intestinal flora. Now my husband has had back pain for some time, and I gave him 5 drops; he didn't believe it would work. After about 30 minutes, he was totally surprised that he no longer had any pain when he got up. That's why I'm now ordering a bottle for him too." (Source: Trustpilot)

Ines G., May 25, 2025

"I love using CBD oil for period pain and mild headaches to avoid pain pills." (Source: Trustpilot)

Daniela W., March 6, 2024

"Headaches without Ibuprofen. And it works faster than any pill, even migraines are under control with it! Absolutely recommended! I've been using the products for 1.5 years." (Source: Trustpilot)

Anne., November 26, 2022

Which CBD product is right for me?

Meanwhile, a variety of CBD products are available legally in pharmacies, drugstores, CBD shops, and online in Germany, Austria, and Switzerland. It currently has the status of a food supplement in Germany and therefore cannot be prescribed by doctors.

For pain therapy, we recommend a product that is as natural as possible, because additives and impurities can have undesirable side effects. In sensitive people, they can also cause headaches.

Full-spectrum oils are the most natural choice. Unlike highly processed extracts, they contain not only cannabidiol but also other valuable cannabinoids, terpenes, and flavonoids from the hemp plant. These substances work even better together than alone – an effect also known as the " entourage effect." CBD oil is best taken sublingually for a faster effect.

However, not everyone is a fan of the typical hemp taste, which is mainly caused by the hemp oil carrier. MCT oil, which we use in most of our products, has a more neutral taste. If you don't like the hemp taste at all, our flavored oils, e.g., with turmeric, might be for you.

When buying, always pay attention to quality. Reputable manufacturers offer full-spectrum oils from organic cultivation that have been tested by independent laboratories. Certificates should be publicly accessible and confirm that the product is free of harmful substances and actually contains the stated CBD content. High-quality CBD oils contain very little THC to avoid unwanted psychoactive effects.

Sounds interesting?

Try CBD oil now.

Discover CBD oils now

Sounds interesting?

Try CBD oil now.

Discover CBD oils now

Our Conclusion: CBD as an Alternative to Painkillers

One thing is clear: taking CBD oil can be a real alternative to conventional painkillers - especially for tension headaches. While common medications like ibuprofen, aspirin, and paracetamol work quickly, they only treat the symptoms and can have significant side effects with prolonged use.

CBD, on the other hand, targets exactly where the real problem often lies with tension headaches: muscle tension, stress, and an overstimulated nervous system. It relaxes muscles, reduces inflammation, alleviates stress, and influences pain perception - all without the long-term risks of conventional painkillers.

Sounds interesting?

Try CBD oil now.

Discover CBD oils now

Sources and Studies

(1) Hakami, A. Y., & Alshehri, F. S. (2025). Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials. Frontiers in pharmacology, 16, 1521792.


(2) Tomaszewska-Zaremba, D., Gajewska, A., & Misztal, T. (2025). Anti-Inflammatory Effects of Cannabinoids in Therapy of Neurodegenerative Disorders and Inflammatory Diseases of the CNS. International journal of molecular sciences, 26(14), 6570.